Not natively. You can only create a 404 which is essentially the same thing.
Great. That's cool.
"The difference between a 404 and a 410 header is simple: 404 means “content not found”, 410 means “content deleted” and is, therefore, more specific. If a URL returns a 410, Google knows for sure you removed the URL on purpose and it should, therefore, remove that URL from its index much sooner."
It seems that 410 is quite different from a 404 and can be useful in certain scenarios. Is there no way to 410 a page in Duda?